Mal-Propionyl-PEG8-Gly-Gly-Phe-Gly-PAB(m-PEG4) dbco-propionyl AggFluor P1 exhibits fluorescence in

AggFluor P1 exhibits fluorescence in both misfolded oligomers and insoluble aggregates but cannot differentiate between these species

417 SMILES OC(=O)CCOCCOCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Nature 2020

CC-92480 promotes rapid and extensive degradation of Aiolos/Ikaros than s lenalidomide and pomalidomide

this product contains a PEG4 linker instead of PEG2

Mal-Propionyl-PEG8-Gly-Gly-Phe-Gly-PAB(m-PEG4) dbco-propionyl AggFluor P1 exhibits fluorescence inSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker