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CC-3060 is a Cereblon modulator and promotes ZBTB16 degradation by primarily engaging distinct structural degrons on CRBN-ZnF1 zinc finger domains
SiR-Azide is a far-red fluorescent probe containg azide moiety for click chemustry apploications
CA-SS-SulfoCy5 is a membrane-impermeable probe that covalently binds to the Halotag
274 Purity (HPLC) >= 95% Solubility DMSO
[2H]C([2H])([2H])N(CCNC)C([2H])([2H])[2H] Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP maleimide CC-3060 is a Cereblon modulatorSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to
