Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan enzyme Product Name tert-butyl N-{4-[4-(2-{4-[2-(2-aminoethoxy)ethyl]piperazin-1-yl}ethyl)piperazin-1-yl]butyl}carbamate Synonyms

Product Name tert-butyl N-{4-[4-(2-{4-[2-(2-aminoethoxy)ethyl]piperazin-1-yl}ethyl)piperazin-1-yl]butyl}carbamate Synonyms CAS Number n/a Related CAS Molecular Formula C23H48N6O3 Molecular Weight 456

SNAP2-TMR CAS Number Related CAS Molecular Formula C37H33ClN6O5 Molecular Weight 677

and stable

403 Purity (HPLC) >= 95% Solubility DMSO

preventing it from forming a covalent bond with the Halo-tag protein

Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan enzyme Product Name tert-butyl N-{4-[4-(2-{4-[2-(2-aminoethoxy)ethyl]piperazin-1-yl}ethyl)piperazin-1-yl]butyl}carbamate SynonymsSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is