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Propargyl-Acetyl-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg DMF Shipping Conditions Room Temperature

SKU 70720177366
4.1
EUR445.00 EUR473.00

Pay in 4 interest-free payments of $111.25 Learn more

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Ships within 48 hours · Estimated delivery Aug 7 - Aug 12

Description

DMF Shipping Conditions Room Temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Lenalidomide-acetamido-O-PEG3-C2-Cl Synonyms Lenalidomide-4'-acetamido-O-PEG3-C2-Cl CAS Number n/a Related CAS Molecular Formula C23H30ClN3O8 Molecular Weight 511

Product Name: Lenalidomide-CO-C1--piperazine HCl Synonyms: CAS Number: Molecular Formula: C19H25Cl2N5O4 Molecular Weight: 458

Product Name Thalidomide-5'-O-PEG2-OH Synonyms CAS Number 2328212-84-4 Related CAS Molecular Formula C17H18N2O7 Molecular Weight 362

Product Name Pomalidomide-5'-PEG5-OH Synonyms CAS Number 2641838-56-2 Related CAS Molecular Formula C23H31N3O9 Molecular Weight 493

Propargyl-Acetyl-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg DMF Shipping Conditions Room TemperatureSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC

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