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DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB Size:10mg 407 SMILES OCCOCCOCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC)

SKU 70725034629
4.6
EUR195.00 EUR241.00

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Description

407 SMILES OCCOCCOCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

MC-Val-Cit-PABC-PNP is a cathepsin-cleavable ADC linker that connects antibodies to cytotoxic payloads through a Val–Cit peptide and PABC spacer

Product Name BC-Biotin Synonyms Biotin-CLIP CAS Number Related CAS Molecular Formula C28H39N7O4S Molecular Weight 569

Product Name Mal-Propionyl-PEG2-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C79H100FN11O25 Molecular Weight 1622

NCCOCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB Size:10mg 407 SMILES OCCOCCOCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing

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