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Product Name Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C56H90N10O20 Molecular Weight 1223
CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCN)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Molecular Glues for Targeted Protein Degradation: From Serendipity to Rational Discovery
Product Name 5(6)-ROX PEG3 azide Synonyms 5-(and 6)-Carboxy-X-rhodamine PEG3 Azide CAS Number N/A Related CAS Molecular Formula C41H46N6O7 Molecular Weight 734
7'-dichlorofluorescein is a fluorescent intracellular pH indicator in the pH 4-5 range
Propargyl-Acetyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:10mg Product Name Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8) Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate
