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Mal-Acetyl-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-Exatecan Thalidomide Product Name Thalidomide-O-C6-OH Synonyms Thalidomide-4'-O-C6-OH

SKU 82183160055
4.5
USD495.00 USD539.00

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Ships within 48 hours · Estimated delivery Aug 22 - Aug 27

Description

Product Name Thalidomide-O-C6-OH Synonyms Thalidomide-4'-O-C6-OH CAS Number 2420490-73-7 Related CAS Molecular Formula C19H22N2O6 Molecular Weight 374

Product Name 4-(methoxy-d3)benzaldehyde Synonyms 4-(²H3)methoxybenzaldehyde CAS Number 342611-04-5 Related CAS Molecular Formula C8H8O2 Molecular Weight 139

In general

Product Name: 5(6)-FAM alkyne Synonyms: 5-(and 6)-carboxyfluorescein

CP-FAM is a SNAP-tag substrate containg 6-fluorescein dye (6-FAM)

Mal-Acetyl-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-Exatecan Thalidomide Product Name Thalidomide-O-C6-OH Synonyms Thalidomide-4'-O-C6-OHSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan,

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