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Product Name Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C56H94N8O21 Molecular Weight 1215
S)-AHPC-CO-C5-NH2 HCl Synonyms CAS Number 2415256-20-9 Related CAS 2170695-19-7 (free base) Molecular Formula C28H43Cl2N5O4S Molecular Weight 616
CP-DBCO is a SNAP-tag substrate containg DBCO moiety for click chemustry apploications
OC(=O)C1=CC=C2C(=O)OC3(C2=C1)C1=CC=C(O)C=C1OC1=C3C=CC(O)=C1 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only
CN1C(=O)C(C)=C2N(C(=O)N(C3CC3)C(=O)C2=C1NC1=C(F)C=C(I)C=C1)C1=CC(N)=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG8)-Exatecan AHPC Product Name Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8) Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I
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